I am an avid Ruger SA fan, and most of my single actions are Rugers. Today I was firing a Ruger and Uberti Flat Top Target alternately and was impressed by how petite the Uberti felt. The Ruger is a big, strong, stout revolver to be sure, but for carry and handiness the Uberti would have a slight edge, and with the Berretta you'd have that with the six-shot capacity.
I do carry a Ruger Blackhawk .44 Special for everyday use, but mine is on the older .357 Magnum three-screw frame. It's only a five shot proposition, but with my .44 Special, double taps are somewhat redundant, anyway.