I think the real problem is a lack of left-handed SHOOTERS! If there were more, we'd have more left-handed guns.
DA revolvers are no problem to shoot (that is, reload) left-handed. One of the top competition revolver shooters in the country is a lefty, and his loading technique is just a bit different from what you see elsewhere.
http://www.youtube.com/watch?v=7YXtmQjSWEo