Justified, are you going to buy a rifle or build one?
(Or have one built)
For one built to your specs you can have many more options.
Factory 50 cals are usually very heavy. Not a problem if you don't have to carry it up a lot of mountains, but for those that do a lot of foot work getting into their hunt areas, a lighter rifle is a wonderful thing.
If you build, you have the options of;
Left or right handed rifle
Type of sights.
Placement of sights
Wood and grade of wood.
And a lot more.