Strafer, I'm not a fan of spine shots.
I once hit high into the spine of a deer. (downhill shot, I misjudged placement)[BTW, this was using a .45 cal. muzzle loader with patched round ball.]
Yes, the deer dropped where it stood but was still very much alive. This was very disturbing as I prefer quick one shot kills. It was the only deer I have had to use a second shot to dispatch.
I thank everyone for all the replies to my question. I have learned a lot. I have decided to stay with my normal heart-lung placement. But, I may consider a neck shot if the circumstances dictate it to be the best choice.