I'm a lefty and you can adapt pretty quickly to a right handed pistol. You will be surprised what you can do just using your index finger so don't feel that you have to have an ambi pistol.
With that said,I will admit though that I had to have an ambi safety on my 1911. I couldn't over come that one.
I might also suggest looking at a Walther PPS. The mag release is ambi and the slide release is easy to work using your index finger on your left hand. If it matters to you, even the PPS that are marked "Smith and Wesson" are made in Germany.
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