I ended up putting my S&W 60 to pasture because of arthritis issues (both wrists and now an elbow - gettin' old sux). Since then, I've been carrying an LCR .22LR. But, as soon as this thing actually hits the streets, the .22LR will fall to second place behind a .22WMR LCR full of Hornady Critical Defense hollow points.
I know it's still not ideal, but I'm at the age where I have to take my warm and fuzzies however I can get them. I just couldn't take the 60 and it's hopping around like a cat on a cactus anymore