Don't know about bears but I have a bit of experience with moose.
When I hired on with the Anchorage Police Dept I was issued a Model 28 Smith, 357. We could only carry 4 in Smiths or Colts.
Later in my career they started allowing us a choice to carry semis so I tried my 1911 (USGI 1911a1) for a while.
We got a lot of moose - vehicle encounters which required the dispatching of wounded moose.
I shot several with my Model 28, zero problems, worked great. But as mentioned I decided to give my 1911a1 a try. We still had moose/vehicle accidents and I found the 45 ACP sucked compared to the 357.
I went back to carrying my Model 28 and never looked back. I like 1911s and I like the 45 ACP round (suited me well in Vietnam) but its not a large animal round in my opinion.
CPT USAR Ret
USAMU Sniper School Oct '78
Distinguished Rifle Badge 1071