I have several 2" S&W's and the Ruger LCR.
I use .38 Special BuffaloBore standard pressure hard lead wad cutters, even in the .357 revolvers.
I carried the S&W Model 640 as my CCL weapon before the LCR.
Now, I only carry the LCR.
I find it lighter, as accurate as the 640, but with a superior action.
As an aside, the LCR has the Crimson Trace grip.
Two big farm dogs attacked me while photographing.
When the laser hit their eyes, they fell over their feet trying to stop.
A real good reason for having the grips!