I only shoot 4 rounds Total. (my wife has a few others but these are mine and what I get ammo for)
1. 22lr: Cheep plinker and good for small game.
2. 357 Magnum: good for self defense and able to take up to deer especially with a carbine.
3. 45-70Govt: yes I have it in a revolver and in two rifles. Power wise the hot loads are between a 454 Casul and 460 Magnum. It can shoot bullets from 250 grain to 550 grain.
4. 12ga: yeah I wish I could find one in a revolver