I don't do a lot of tuning to my Rugers, but do sort of customize them. Here is my three-screw Super Blackhawk, cut to 5" and with the Blackhawk hammer, which I prefer, and color cased byn Doug Turnbull:
And here is a .45 Colt Blackhawk built up as a Bisley:
Contrary to what most other shooters say, the Bisley didn't work for me with heavy loads, so this gun is now back to a Blackhawk.
Here it is converted back to Blackhawk, with my very favorite .45 with the Super Blackhawk grip frame, my favorite for heavy .45 Colt loads:
You can do so much with a Ruger, or any other single action, for that matter.