As a Bouncer for 5 years in Liverpool UK, was in lots of fights, lots. Best way to win, start first.
Person you can reach with your hands, just a single step away, I own him.
But if you had to resort to bullets? You had better have drawn and fired from concealment, the same holster, same pistol, a whole bunch.
Hit with one hand, or both, close up, under 10m, hitting body mass, whilst moving, not impossible.
But you had still have had to ask yourself that question? Could I shoot someone, multiple times? Oh yes, I did not travel this earth for 77 years to have some low life end said life, not without a fight.