cast bullet..... I shot some, dime sized groups at 7 yards (common PD range) out of a 6" python... gruesome effect on target.
The same load from you 6" python vs a 2" snubbie is about 200-250 FPS difference. Like night and day at those velocities. I had good results with My Marlin and wadcutters on skunks, but you had to load 1 at a time because the gun did not feed them.