Before the internet lots of things worked just fine. My .22 Hornet has never had a problem taking down a coyote. It is legal for deer in MO as well, and I did actually take a deer with it, passed on several until I had one that met my requirements, and I will say this I was quite under impressed with it on deer, but she dropped at 50 yards with a bullet into the white patch under her throat. (I expected shattered neck vertabrae, but didn't get it).
As with all cartridges keep it within its and your effective range, feed it good bullets designed for the task and watch it work. Mine loves 45 grain HP's loaded to a moderate level, any hotten and it will split the case necks, which is a terrible sin for reloaders.