I wonder about that ripnbst-only because of multiple threats. I have the Ruger sp101 and I have .357 ammo loaded in that gun. The problem is that in a case with 3 or even maybe 4 enemies coming at me in a parking lot-I would not be capable of getting off more than ..say.. 2 rounds in a matter of seconds. I know because I have tried it. The trigger pull on the sp101 makes it difficult for me to accurately shoot more than 2 shots quickly.
I am surely not that experienced-but I do like lots of rounds that I can get off in a hurry-if need be.