"If the VV 110 is anything like H-110, Mag primers are a necessity for max velocity and uniform pressure."
Aside from the same applications N110 is nothing like H110. H110 is a double base fine ball powder that cannot be downloaded or compressed and requires magnum priming for proper ignition. N110 is a single base fairly fine extruded powder, a little coarser than H322 but finer than Varget. It can be downloaded, I've seen published data in 38 Special with N110, and it can be compressed. Recommended priming with N110 in published data is all over the map. In my experience and from what I can tell from published data N110 does not require magnum priming but it doesn't hurt it either.