I shoot the .44 Spl in a Ruger Superblackhawk and a model 24. The Ruger is more accurate. I favor a Lee 208 WC bullet with 6.0 of Promo...gives about 1,000 FPS and is an excellent plinking round. So why not just load in a .44 Magnum case...the shorter case offers better consistency.
BTW the cylinder will gunk up with the load--very easy to clean...chuck and old brush that is wrapped with with copper Chore Boy or 0000 steel wool and spin in a drill. Takes but seconds...one can do the same shooting .38's in a .357 Mag.