I paid $1400.00 for my first. I was for a 45-70. The more uncommon the more it will cost you. 22 suppressors are very cheep compared to center-fire and common center fire such as 22 or 30 caliber are much cheaper than less common calibers .458, 50
Shot placement is everything! I would rather take a round of 50BMG to the foot than a 22short to the base of the skull.
all 21 of my guns are 45/70 govt 357 mag, 22 or 12 ga... I believe in keeping it simple