A LOT of it depends on powder type, as well.
IMR powders have always had a reputation (born out in my semi-extensive experience with them in a number of rifle cartridges) as being VERY forgiving and capable of still producing extremely fine accuracy even with fairly wide deviations in charge weight.
Hatcher mentions that in his Notebook, as well.
Consistent powder positioning and density is apparently a lot more important.
"The gift which I am sending you is called a dog, and is in fact the most precious and valuable possession of mankind" -Theodorus Gaza
Baby Jesus cries when the fat redneck doesn't have military-grade firepower.