Yes, you can go from .45 to .10mm. But why would you change out to go hiking. For a little more capacity?
.45 doesn't provide anywhere near the amount of energy of penetration as a 10mm... .45 is great for 2 legged critters... not so much for 4 legged ones.
Glock 19 G4 Gray | Glock 17 G4 FDE | S&W M&P 22 | S&W M&P 45 | S&W M&P 9 | S&W M&P Shield 9
Sig P226 MK25 | Sig P229 Extreme | Sig P320 F | Sig P320 C | HK USP 9 | HK USP 45 | HK USP 45 (Tan) | HK VP9
Daniel Defense DDM4 V4 | Arsenal SGL 21 | ASA SBR | Savage Mark II FV-SR
Mossberg 590A1 20" SP | Mossberg 500 Cruiser