If you are planning to shoot mostly .44 Special in your .44 Magnum, and once in a while use it as a "woods gun" with full house loads, you may encounter accumulations of lead/crud and/or cylinder erosion in the area just forward of the shorter .44 Special cases.
I haven't experienced this yet because -
1. I'm a relatively new .44 Magnum revolver owner, and
2. I use high end .44 Special loads in .44 Magnum cases if I don't want to shoot at Magnum velocities.
I believe the lead/crud problem can cause problems in chambering and the erosion problem can cause problems in extraction. Both of which will go unnoticed until you try to shoot the longer .44 Magnum cases.
.30-06 Springfield: 100 yrs + and still going strong