My choice would be one of the S&W 38s. A little more power than the Astra 380 and the auto without one in the chamber is useless IMO. I can't see much to go wrong with a S&W except maybe another squib incident.
I carry a S&W 642 5-shot and love it. I also carry a LCP 380 auto, but if I couldn't carry one in the chamber I would get rid of it (or use it for a paperweight
BTW, it seems you have four options listed rather than two.