My wife wouldn't ever carry . . . but I have a friend I shoot with - she's petite and about 5' tall. She has a Sig .380 and is deadly accurate with it. Thee are lots of good .380 pocket guns out there - S & W Bodyguard, Kahr, Ruger LCP . . . and as has already been said . . . shot placement is everything along with practice, practice, practice . . . .
If a pair of '51 Navies were good enough for Billy Hickok, then a single Navy on my right hip is good enough for me . . . besides . . . I'm probably only half as good as he was anyways. Hiram's Rangers Badge #63