DANGER, Will Robinson!
RC20 is well intentioned but wrong in his assertion of complete safety in starting in the middle of a load range. It depends on the powder and other components involved in the recommended range. I've twice in my life encountered loads at the bottom end of a recommended range that turned out to hard maximums for the guns I was using them in.
You don't need a lot of effort to work up. A general recommendation is 2% steps. So if a load range starts at the usual 10% below maximum, you have only 6 rounds to go to maximum, while looking for overt pressure signs. It's not worth not doing it, just in case you've got one of those peculiar combinations in hand.
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