I've used IMR4350 with Hornady 180 gr. SST's with a little bit of success out of a Remington 700. Managed to get 3/4 inch groups at 100 with it, haven't had a chance to stretch them out as far as you plan to, though. My brother used the 700 to take a whitetail with this load last weekend, he said it was pretty effective!
My $0.02
Cheers!
McClintock