I bought a new Model 22, four or five years ago, and it printed - with my handload of choice - a foot low and six inches right, at twenty-five yards. After filing the sight on top and one side, it was dead-on . . . with my load . . . with me doing the shooting . . . at 25 yards.
Change the shooter, the load, or the distance, and it won't print the same.
When the "modern" double action revolver was invented, 120 years ago, most calibers had a single load, so it wasn't such a big deal to have fixed sights; all .38 Spl. loads were 158 @750. Today, you either have to have adjustable sights, find the load that matches you and your sights, or get out the file.