I've been reloading for 8 years, .44mag, .357mag and .45acp.
I never chamfer, and I don't own a case trimmer.
The loads are super accurate, and I've killed several deer with the 44 loads from 5 yards, out to 85 yards, with a handgun.
Oh, and I only use Unique powder! This supposedly isn't a good powder for deer loads. My dead deer would disagree.
Do whatever works for you, within the established safety guidelines, of course. I like to keep it simple.