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The 10mm may pen 10" deeper then the 45acp but the 45acp is making a much bigger hole ..
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.051 of an inch bigger!
Speed kills. A Chevy moving at 1/2 mile an hour may knock you down but it won't kill.
The 10mm with 180-200g bullets would be a great choice for a woods gun if heavier revolvers are not a option.