I've loaded over 25K rounds on a Lock and Load. I must say I have tweaked all the issues out of it and it runs great for me. It cost a heck of a lot less than the Dillon too.
The Dillon (650) is no doubt an excellent machine, but it has a few warts too.
The primer cup is a PITA, I like the mod to have a primer receptacle. Changeovers are expensive too. I wish they would include a better powder adjustment. I will admit to constantly pricing and admiring the 650 though
I built some LED lights for me and my buddies, a necessary add on IMO.