I think I always come out ahead with Powder Valley when I order at least 5k in primers and 4 lb of powder per order. Normally I will get 10 k or more primers and 12 lb of powder to last for a while. I know I can't beat those prices even with HAZ-MAT and shipping added locally or at the gun shows. When ever I am interested in trying a different brand of primer or powder I just add what I want to try to my next order. I have been able to pick up those things at a much lower price than I can locally. Also locally it is hit or miss to find what I might want to get.
Buying bulk amounts of bullets on line is also providing me some savings.