I like that the M&P series is available just like a Glock - zero extraneous safety features, no mag safety, no manual safety, no physical LCI, but also available with those options if you want them.
If you do want all the safety options, I'd consider the two pistols basically the same with the slight edge to the M&P for having acquitted itself well in a service context.
Beretta PX4 .40 S&W | Beretta 92FS 9x19 Para | Rock Island Armory GI 1911 .45 ACP | Colt Python 4" .357 Magnum | Colt 1968 Det. Spec. .38 Spc. | Ruger LCP .380 ACP | Daniel Defense M4V1 5.56x45 | Alpine M1 Carbine .30 | Steyr M1895 8x56 | Ruger 10/22 .22LR |1943 Izhevsk Mosin-Nagant M91/30 7.62x54R | Remington 870 12GA