A 280 won't do anything a 30-06 or 270 won't do in reality, but it isn't a handicap either. If you handload you can very slightly do better than either, at least on paper. I've had a couple over the years and I'm not convinced anything you shoot will know the difference.
If you handload it is a great round that lets you shoot something a little different from the crowd. I wouldn't fool with it if I had to buy factory ammo.
I like the rifle BTW. Price seems a little high, but not horrible if in good shape.