what I recommend is carrying in a holster that is designed for carrying the gun you like but carry in a position that if you for some odd reason do have an AD/ND it does the minimal amount of damage like on the hip area or in a cross draw. No one wants to bleed to death because they have a gun pointed at a major artery and hits the trigger.
IMO carrying a gun is not fashionable or convenient, it is a life choice and when you make that choice you have to give up comfort for peace of mind. I had a little 380 and I carried in an IWB ace case tuckable holster. Just as fast as a pocket holster but pointed away from all the main blood vessels