I reload as long as its fun. Typically about an hour to 90 min. When I get tired of it I stop. But its not unheard of for me to have multiple session in the same day.
I find it much easier to reload for a long time when there is some thing else I need to do but don't want to do it
Shot placement is everything! I would rather take a round of 50BMG to the foot than a 22short to the base of the skull.
all 25 of my guns are 45/70 govt, 357 mag, 22 or 12 ga... I believe in keeping it simple