When big game hunting in the Rocky Mountains I have always carried a S&W
.357 mag ( model 28 in 6" )....in an outside the waist band...typical western holster with a security strap over the hammer to keep the gun in the holster if I fell.
If I didn't have the model 28 / I'd probably carry an L frame model 686 in 6".
Once in a while, when I knew I was in fairly heavily populated Grizzly country / I'd carry a S&W model 29 6" .44 mag..../ same rig (since its an N frame like the model 28 ).
Fly fishing in the same areas....I always carried the same gun in a shoulder rig - to keep it up out of the water when I was wading in a lake or river...