I use Win748 for 35gr Nosler bullets in 22-250 and I would highly recommend it for that purpose. I assume 40gr would be similar.
I get 4,435fps from a 24" barrel and it's at least 2 steps below max charge. 1/2 MOA accuracy at 100, or better, rarely shot for groups but regularly killing woodchucks at 300 or better.
Still happily answering to the call-sign Peetza.
You do not HAVE a soul. You ARE a soul. You HAVE a body.
He is no fool who gives what he can not keep to gain what he can not lose.
-Jim Eliott, paraphrasing Philip Henry.