Can't help but think that your cylinder is not locking up with the chambers matching the barrel. I'm shooting a Ruger Super Blackhawk not a Hunter and I use iron sights only but everything from 44 spcl powder puff loads to Double tap 300 gr loads shoot to where I want them. If everything is solid and the barrel looks good then you should be able to do the same thing. Ruger or real good pistol smith your choice but I wouldn't do anything to it that might make Ruger think you messed it up with your tinkering with it. Just dos centavos from an old dinosaur.
Good intentions will always be pleaded for any assumption of power. The Constitution was made to guard the people against the dangers of good intentions. There are men in all ages who mean to govern will, but they mean to govern. They promise to be good masters, but they mean to be masters.