If I want to shoot a gun that size, and am worried about 4-legged, fanged things, I have a 6" 629 which beats both the .357 and the 10mm by quite a margin (typically loaded with 255gr Keith HC Buffalo Bore, for woodland use).
I can shoot buffalo bores that just might blow up a 629 with a BB 340G +P+ at 1450fps out of my Ruger RH. What your point?
I can get a Dillon 9X25MM 125g can shoot a 125g at 1700 FPS at 800+lbs.
These of which nobody here obviously doesn't acknowlege or respects the dillon.
I know about energy dumb is quicker out of a lighter load.