The data suggests, as Brian mentioned, that pressure is a key factor in hearing damage. For that reason I favor a lower pressure cartridges shooting heavy, slower bullets for home defense, such as .38 special, .44 special and .45 ACP. .45 Colt would also be a good choice. A .357 mag snubbie is just about the worst choice you can make hearing-wise.
My guns include S&W and Colt revolvers, Colt and Ruger pistols, Remington 870 shotgun, Henry and Marlin .22LR rifles, Hi-Point 9mm carbine and Lancaster Arms AK. I reload handgun rounds with a Lee hand press, over 18K rounds since Nov. 2009 with nary a squib nor kaboom.