A group of 5 who all have guns? Probably not.
A group of 5 where one or two have guns, and the others have fists, knives, or clubs? Possibly.
A group of 5 who don't have guns. Odds get somewhat better.
Of course, the ability to use cover and concealment, to move, to use one's body as a weapon as necessary, to use a member or members of the group as barriers between oneself and the other members of the group would all be factors that could increase the odds of surviving / winning.
Or, one could just assume one can never beat a group of 5... in which case, one can't.