Doc, the terrain varies. You can have up to and beyond 1000 yard shots in bottom land to some thick stuff that will limit shots to near point blank and anything in between.
Most states hunting regs tell you the minimum caliber, FPS, ft# and powder charge.
Tennessee regs only require .36 caliber and higher for big game (black powder, any centerfire for modern), rifle or handgun.
I believe I will hit the range tomorrow (didn't make it today) and work up some loads and put myself and the Dragoon through the paces.