For m any years my daily carry gun was my S&W Model 19. Then, in the fall of 2010 I shot off my mouth about the general unsuitability of carrying a single action as a daily sidearm. Folks over on the Ruger forum challenged me on that, and I realized I had never really tried it.
So, I got my Ruger Blackhawk .44 Special and a Bob Mernickle PS-6 SA holster and gave it a try. Don't think I'll ever go back to a small bore revolver.
A .44 caliber 240 gr. SJHP at around 925 fps is a lot more comforting to me.