the easiest way to answer that question is to give heritage a call and talk with them - they of all people ought to be able to answer your questions/concerns. I have a Heritage RR and love it. A lot of folks knock them but mine is accurate and well made for the price. I son't have any experience with the big bores but based on my experiences with my RR, I wouldn't have any hesitation in trying one.
If a pair of '51 Navies were good enough for Billy Hickok, then a single Navy on my right hip is good enough for me . . . besides . . . I'm probably only half as good as he was anyways. Hiram's Rangers Badge #63