I shoot my .38 Airweight snub with GDHP 135g +P and about 20-24" low of CM at 50 yards, and get very close hit's to CM. That's up and down not side to side, that's all me.
But that might be the way I line up my sites. I let a guy shoot the same gun at 50 and told him to shoot low. He shot about the same to CM.