"what cartridges have you become disenchanted with over the years ??? "
38 spl - would not shoot it at all if not for J-frames, but they feel great, shoot very accurately.
.357 Mag - can't explain it, have got to the point where it has become preferable to shoot 44 Mag.
9mm - has become just like 22 LR, just plain boring, and there aren't any exciting 9mm handguns out there anymore, and the ones I really like (ie CZ 75, Beretta 92, HK P2000, Walther P99) I can't shoot accurately.
For 20 years the sea was my home, always recall the sun going down, and my trusty friend, a 1911 pistol, strapped to my side.