I have at least 3 guns each ( Sigs or 1911's ), in semi-auto calibers of
(.22, 9mm, .40S&W, .45 acp ) and S&W & Freedom Arms revolvers in (.22,
.38 spl, .357 mag and .44mag....)
and its not that I've fallen out of favor with any of them ...
a. but I shoot very little of .38 spl / preferring instead to shoot .357 mag ..../letting the grandkids primarily shoot the .38 spl I load.
b. and I shoot very little of .40S&W ...although I have carry guns in that caliber and a nice 1911 as well..../ instead I shoot a lot of 9mm and .45ACP.
c. I don't shoot a lot of .22 / because I can reload 9mm for under $5 a box ...and premium .22 ammo is over $10 for a box of 100...
and since I reload all of my calibers...it isn't really the cost differential that matters much at all to me.../ I kind of run in cycles....and one of these days I'll decide its a .40S&W day at the range ...and take 3 or 4 guns in .40S&W to the range...just for the heck of it ....