it does not hurt guns (springs ect.) to leave them loaded.
you may want to rotate your ammo every six months or so.
then again a true gun owner will check there weapons at least every once in a while for that may save your life when you least expect it.
of course some will say if you have children you shouldn't; and if you do, lock them and put them away.
we were taught as children that all guns are loaded.
we were also taught all guns were destructive TOOLS and not play toys.