I have always enjoyed developing a load for a specific rifle. Have tried many combinations of powders and bullets of 100 gr or more in the 25-06.
Having experimented with the 25-06. My preferered accuracy load is using Sierra 100gr bullets and 54.5 or 55.5 Reloader 22.
IMHO, the lighter grain bullets are OK, but if you do a considerable amount of shooting with the lighter bullets at speeds over 3500fps or greater, barrel wear is a certainty.