Being the RO of a small range with a well-behaved bunch of shooters, I had the opportunity to try many non-action styles of shooting.
I spent several sessions trying the gangsta hold on the 50' range. One can learn to hit accurately that way but with fixed sights you have to hold over and to one side to get the hits where you want them. That's what you'd expect from turning the gun 90 degrees from the way it was designed to work.
On the other hand, having had to go to ground on my side and shoot targets during a stage at an IPSC match, I know that for close range I can shoot from lying on my side with a 2 hand hold and use the sights just like normal and get A zone hits.