I live and hunt in Idaho. Here we have lots of big game if you know where to look.
One thing not typical about where I hunt is that it is heavily forested. Along shot here is 100 yards unless you are hunting recently burned off areas from fires.
Shot placement is everything! I would rather take a round of 50BMG to the foot than a 22short to the base of the skull.
all 26 of my guns are 45/70 govt, 357 mag, 22 or 12 ga... I believe in keeping it simple. Wish my wife did as well...