If they fit they are comfortable period. I have Pachmayr on my 41 mag and they are great, I have custom wood grips on my Dan Wesson .357 and they are great, same with my over sized wood target grips on my S&W 41. Only Gun I have I would like to change grips on is my Ruger Super Blackhawk, larger grips would be better. Plastic, wood, or rubber makes no difference to me if the gun fits in my hands.
Good intentions will always be pleaded for any assumption of power. The Constitution was made to guard the people against the dangers of good intentions. There are men in all ages who mean to govern will, but they mean to govern. They promise to be good masters, but they mean to be masters.